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IFReC 大阪大学 免疫学フロンティア研究センター

RIMD 大阪大学 微生物病研究所

© 2023 Akira Lab.
Host Defense, WPI Immunology Frontier Research Center (IFReC), Osaka University
Department of Host Defense, Research Institute for Microbial Diseases, Osaka University

業績Publications

  1. Hoshino K, Takeuchi O, Kawai T, Sanjo H, Ogawa T, Takeda Y, Takeda K, Akira S. 1999.
    Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product.
    J Immunol 162: 3749-52
  2. Kawai T, Adachi O, Ogawa T, Takeda K, Akira S. 1999.
    Unresponsiveness of MyD88-deficient mice to endotoxin.
    Immunity 11: 115-22
  3. Takeuchi O, Hoshino K, Kawai T, Sanjo H, Takada H, Ogawa T, Takeda K, Akira S. 1999.
    Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components.
    Immunity 11: 443-51
  4. Hemmi H, Takeuchi O, Kawai T, Kaisho T, Sato S, Sanjo H, Matsumoto M, Hoshino K, Wagner H, Takeda K, Akira S. 2000.
    A Toll-like receptor recognizes bacterial DNA.
    Nature 408: 740-5
  5. Yamamoto M, Sato S, Hemmi H, Sanjo H, Uematsu S, Kaisho T, Hoshino K, Takeuchi O, Kobayashi M, Fujita T, Takeda K, Akira S. 2002.
    Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4.
    Nature 420: 324-9
  6. Yamamoto M, Sato S, Hemmi H, Hoshino K, Kaisho T, Sanjo H, Takeuchi O, Sugiyama M, Okabe M, Takeda K, Akira S. 2003.
    Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway.
    Science 301: 640-3
  7. Akira S, Uematsu S, Takeuchi O. 2006.
    Pathogen recognition and innate immunity.
    Cell 124: 783-801
  8. Matsushita K, Takeuchi O, Standley DM, Kumagai Y, Kawagoe T, Miyake T, Satoh T, Kato H, Tsujimura T, Nakamura H, Akira S. 2009.
    Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay.
    Nature 458: 1185-90
  9. Satoh T, Kidoya H, Naito H, Yamamoto M, Takemura N, Nakagawa K, Yoshioka Y, Morii E, Takakura N, Takeuchi O, Akira S. 2013.
    Critical role of Trib1 in differentiation of tissue-resident M2-like macrophages.
    Nature 495: 524-8
  10. Uehata T, Iwasaki H, Vandenbon A, Matsushita K, Hernandez-Cuellar E, Kuniyoshi K, Satoh T, Mino T, Suzuki Y, Standley DM, Tsujimura T, Rakugi H, Isaka Y, Takeuchi O, Akira S. 2013.
    Malt1-induced cleavage of regnase-1 in CD4(+) helper T cells regulates immune activation.
    Cell 153: 1036-49
  11. Satoh T, Kidoya H, Naito H, Yamamoto M, Takemura N, Nakagawa K, Yoshioka Y, Morii E, Takakura N, Takeuchi O, Akira S. 2013.
    Critical role of Trib1 in differentiation of tissue-resident M2-like macrophages.
    Nature 495: 524-8