0937. Kozaki T, Takahama M, Misawa T, Matsuura Y, Akira S, Saitoh T.
Role of zinc-finger antiviral protein in host defense against Sindbis virus.
Int Immunol. 2015 Jul;27(7):357-364. doi:10.1093/intimm/dxv010. Epub 2015 MAr 10.
PMID:25758257
0936. Matsuda T, Murano N, Katano Y, Juliandi B, Kohyama J, Akira S, Kawai T, Nakashima K.
TLR9 signalling in microglia attenuates seizure-induced aberrant neurogenesis in the adult hippocampus.
Nat Commun. 2015 Mar 9;6:6514. doi:10.1038/ncomms7514.
PMID:25751136
0935. Pandey S, Kawai T, Akira S.
Microbial sensing by toll-like receptors and intracellular nucleic acid sensors.
Cold Spring Harb Perspect Med. 2015 Jan;5(1):a016246.
PMID:25713826
0934. Maruyama K, Fukasaka M, Uematsu S, Takeuchi O, Kondo T, Saitoh T, Martino M, Akira, S.
5-azacytidine-induced protein 2(AZI2) regulates bone mass by fine-tuning osteoclast survival.
J Biol Chem. 2015 Apr 10;290(15):9377-9386. doi:10.1074/jbc.M114.631374. Epub 2015 Feb 17.
PMID:25691576
0933. Yamazaki S, Akira S, Sumimoto H.
Glucocorticoid augments lipopolysaccharide-induced activation of the IkBζ-dependent genes encoding the anti-microbial glycoproteins lipocalin 2 and pentraxin 3.
J Biochem. 2015 May;157(5):399-410. doi:10.1093/jb/mvu086. Epub 2014 Dec 30.
PMID:25552549
0932. Patel MN, Bernard WG, Milev NB, Cawthorn WP, Figg N, Hart D, Prieur X, Virtue S, Hegyi K, Bonnafous S, Bailly-Maitre B, Chu Y, Griffin JL, Mallat Z, Considine RV, Tran A, Gual P, Takeuchi O, Akira S, Vidal-Puig A, Bennett MR, Sethi JK.
Hematopoietic IKBKE limits the chronicity of inflammasome priming and metaflammation.
Proc Natl Acad Sci U S A. 2015 Jan 13; 112(2):506-511. doi:10.1073/pnas.1414536112. Epub 2014 Dec 24.
PMID:25540417
0931. Kitai Y, Takeuchi O, Kawasaki T, Ori D, Sueyoshi T, Murase M, Akira S, Kawai T.
Negative regulation of MDA5-dependent antiviral innate immune responses by Arl-like protein 5B.
J Biol Chem. 2015 Jan 9;290(2):1269-1280. doi:10.1074/jbc.M114.611053. Epub 2014 Dec 1.
PMID:25451939
0930. Atif SM, Lee SJ, Li LX, Uematsu S, Akira S, Gorjestani S, Lin X, Schweighoffer E, Tybulewicz VL, McSorley SJ.
Rapid CD4+ T-cell responses to bacterial flagellin require dendritic cell expression of Syk and CARD9.
Eur J Immunol. 2015 Feb; 45(2):513-524. doi:10.1002/eji.201444744. Epub 2014 Dec 8.
PMID:25430631 
0929. Shi X, Zhang Z, Zhan X, Cao M, Satoh T, Akira S, Shpargel K, Magnuson T, Li Q, Wang R, Wang C, Ge K, Wu J.
An epigenetic switch induced by Shh signalling regulates gene activation during development and medulloblastoma growth.
Nat Commun. 2014 Nov 5;5:5425. doi:10.1038/ncomms6425.
PMID:25370275
0928. Pandey S, Kawai T, Akira S.
Microbial Sensing by Toll-Like Receptors and Intracellular Nucleic Acid Sensors.
Cold Spring Harb Perspect Biol. 2014 Oct 9; 7(1). pii:a016246. doi:10.1101/cshperspect.a016246. Review.
PMID:25301932
0927. Soni C, Wong EB, Domeier PP, Khan TN, Satoh T, Akira S, Rahman ZS.
B Cell-Intrinsic TLR7 Signaling Is Essential for the Development of Spontaneous Germinal Centers.
J Immunol. 2014 Nov 1; 193(9):4400-4414. doi:10.4049/jimmunol. 1401720. Epub 2014 Sep 24.
PMID:25252960
0926. Franchi L, Eigenbrod T, Munoz-Planillo R, Ozkurede U, Kim YG, Chakrabarti A, Gale M Jr, Silverman RH, Colonna M, Akira S, Nunez G.
Cytosolic Double-Stranded RNA Activates the NLRP3 Inflammasome via MAVS-Induced Membrane Permeabilization and K+ Efflux.
J Immunol. 2014 Sep 15. pii:1400582. [Epub ahead of print]
PMID:25225670
0925. Kagoya Y, Yoshimi A, Tsuruta-Kishino T, Arai S, Satoh T, Akira S, Kurokawa M.
JAK2V617F-positive myeloproliferative neoplasm clones evoke paracrine DNA damage to adjacent normal cells through secretion of lipocalin-2.
Blood. 2014 Sep 12. pii:blood-2014-04-570572. [Epub ahead of print]
PMID:25217696
0924. Goto Y, Obata T, Kunisawa J, Sato S, Ivanov II, Lamichhane A, Takemiya N, Kamioka M, Sakamoto M, Matsuki T, Setoyama H, Imaoka A, Uematsu S, Akira S, Domino SE, Kulig P, Becher B, Renauld JC, Sasakawa C, Umesaki Y, Benno Y, Kiyono H.
Innate lymphoid cells regulate intestinal epithelial cell glycosylation.
Science. 2014 Sep 12;345(6202):1254009. doi:10.1126/science. 1254009. Epub 2014 Aug 21.
PMID:25214634
0923. Stockinger S, Duerr CU, Fulde M, Dolowschiak T, Pott J, Yang I, Eibach D, Backhed F, Akira S, Suerbaum S, Brugman M, Hornef MW.
TRIF Signaling Drives Homeostatic Intestinal Epithelial Antimicrobial Peptide Expression.
J Immunol. 2014 Sep 10. pii:1302708. [Epub ahead of print]
PMID:25210121
0922. Ntziachristos P, Tsirigos A, Welstead GG, Trimarchi T, Bakogianni S, Xu L, Loizou E, Holmfeldt L, Strikoudis A, King B, Mullanders J, Becksfort J, Nedjic J, Paietta E, Tallman MS, Rowe JM, Tonon G, Satoh T, Kruidenier L, Prinjha R, Akira S, Van Vlierberghe P, Ferrando AA, Jaenisch R, Mullighan CG, Aifantis I.
Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia.
Nature. 2014 Aug 17. doi: 10.1038/nature13605. [Epub ahead of print]
PMID:25132549
0921. Reynolds LA, Harcus Y, Smith KA, Webb LM, Hewitson JP, Ross EA, Brown S, Uematsu S, Akira S, Gray D, Gray M, MacDonald AS, Cunningham AF, Maizels RM.
MyD88 Signaling Inhibits Protective Immunity to the Gastrointestinal Helminth Parasite Heligmosomoides porygyrus.
J Immunol. 2014 Sep 15; 193(6):2984-2993. doi:10.4049/jimmunol. 1401056. Epub 2014 Aug 11.
PMID: 25114104
0920. Tartey S, Matsushita K, Vandenbon A, Ori D, Imamura T, Mino T, Standley DM, Hoffmann JA, Reichhart JM, Akira, S, Takeuchi O.
Akirin2 is critical for inducing inflammatory genes by bridging IkB-ζ and the SWI/SNF complex.
EMBO J. 2014 Aug 8. pii:e201488447. [Epub ahead of print]
PMID: 25107474
0919. Inokuchi-Shimizu S, Park EJ, Roh YS, Yang L, Zhang B, Song J, Liang S, Pimienta M, Taniguchi K, Wu X, Asahina K, Lagakos W, Mackey MR, Akira S, Ellisman MH, Sears DD, Olefsky JM, Karin M, Brenner DA, Seki E.
TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis.
J Clin Invest. 2014 Aug 1; 124(8):3566-3578. doi: 10.1172/jCI74068. Epub 2014 Jul 1.
PMID:24983318
0918. Hemmi M, Tachibana M, Tsuzuki S, Shoji M, Sakurai F, Kawabata K, Kobiyama K, Ishii KJ, Akira S, Mizuguchi H.
The Early Activation of CD8(+) T Cells Is Dependent on Type I IFN Signaling following Intramuscular Vaccination of Adenovirus Vector.
Biomed Res Int.  2014; 2014:158128. doi:10.1155/2014/158128. Epub 2014 May 27.
PMID:2497131
0917. Choi J, Park S, Biering SB, Selleck E, Liu CY, Zhang X, Fujita N, Saitoh, T, Akira, S, Yoshimori T, Sibley LD, Hwang S, Virgin HW.
The Parasitophorous Vacuole Membrane of Toxoplasma gondiils Targeted for Disruption by Ubiquitin-like Conjugation Systems of Autophagy.
Immunity. 2014 Jun 19; 40(6):924-935. doi:10.1016/j.immuni.2014.05.006. Epub 2014 Jun 12.
PMID:24931121
0916. Huang B, Takahashi K, Jennings EA, Pumtang-On P, Kiso H, Togo Y, Saito K, Sugai M, Akira S, Shimizu A, Bessho K.
Prospective signs of cleidocranial dysplasia in Cebpb deficiency.
J Biomed Sci. 2014 May 13; 21(1):44. doi:10.1186/1423-0127-21-44.
PMID: 24885110
0915. Leung YH, Nicholls JM, Ho CK, Sia SF, Mok CK, Valkenburg SA, Cheung P, Hui KP, Chan RW, Guan Y, Akira S, Peiris JS.
Highly pathogenic avian influenza A H5N1 and pandemic H1N1 virus infections have different phenotypes in Toll-like Receptor (TLR) 3 knock-out mice.
J Gen Virol. 2014 Sep;95(Pt9):1870-1879. doi:10.1099/vir.0.066258-0. Epub 2014 May 30.
PMID:24878639
0914. Shinohara H, Behar M, Inoue K, Hiroshima M, Yasuda T, Nagashima T, Kimura S, Sanjo H, Maeda S, Yumoto N, Ki S, Akira S, Sako Y, Hoffmann A, Kurosaki T, Okada-Hatakeyama M.
Positive feedback within a kinase signaling complex functions as a switch mechanism for NF-κB activation.
Science. 2014 May 16;344(6185):760-764. doi:10.1126/science. 1250020.
PMID:24833394
0913. Zhao H, Aoshi T, Kawai S, Mori Y, Konishi A, Ozkan M, Fujita Y, Haseda Y, Shimizu M, Kohyama M, Kobiyama K, Eto K, Nabekura J, Horii T, Ishino T, Yuda M, Hemmi H, Kaisho T, Akira S, Kinoshita M, Tohyama K, Yoshioka Y, Ishii KJ, Coban C.
Olfactory plays a key role in spatiotemporal pathogenesis of cerebral malaria.
Cell Host Microbe. 2014 May 14; 15(5):551-563. doi:10.1016/j.chom.2014.04.008.
PMID:24832450
0912. Stremnitzer C, manzano-Szalai K, Starkl P, Willensdorfer A, Schrom S, Singer j, Reichart U, Akira S, Jensen-Jarolim E.
Epicutaneously applied Der p 2 induces a strong TH 2-biased antibody response in C57BL/6 mice, independent of functional TLR4.
Allergy. 2014 Jun; 69(6):741-751. doi:10.1111/all.12399. Epub Apr 16.
PMID:24735481
0911. Kurashima Y, Amiya T, Fujisawa K, Shibata N, Suzuki Y, Kogure Y, Hashimoto E, Otsuka A, Kabashima K, Sato S, Sato T, Kubo M, Akira S, Miyake K, Kunisawa J, Kiyono H.
The Enzyme Cyp26b1 Mediates Inhibition of Mast-Cell Activation by Fibroblasts to Maintain Skin-Barrier Homeostasis.
Immunity. 2014 Apr 17; 40(4):530-541. doi: 10.1016/j.immuni.2014.01.014. Epub 2014 Apr 10.
PMID:24726878
0910. Imanishi T, Ishihara C, Badr Mel S, Hashimoto-Tane A, Kimura Y, Kawai T, Takeuchi O, Ishii KJ, Taniguchi S, Noda T, Hirano H, Brombacher F, Barber GN, Akira S, Saito T.
Nucleic acid sensing by T cells initiates Th2 cell differentiation.
Nat Commun. 2014 Apr 10; 5:3566. doi:10.1038/ncomms4566.
PMID:24717539
0909. Kuniyoshi K, Takeuchi O, Pandey S, Satoh T, Iwasaki H, Akira S, Kawai T.
Pivotal role of RNA-binding E3 ubiquitin ligase mEX3C in RIG-I-mediated antiviral innate immunity.
Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):5646-5651. doi:10.1073/pnas.1401674111. Epub 2014 Mar 27.
PMID:24706898
0908. Schmolke M, Patel JR, de Castro E, Sanchez-Aparicio MT, Uccellini MB, Miller JC, Manicassamy B, Satoh T, Kawai T, Akira S, Merad M, Garcia-Sastre A.
RIG-I Detects mRNA of Intracellular Salmonella enterica Serovar Typhimurium during Bacterial Infection.
MBio. 2014 Apr 1; 5(2):. pii:e01006-14. doi: 10.1128/mBio.01006-14.
PMID:24692634

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