0623. Amiel E, Alonso A, Uematsu S, Akira S, Poynter ME, Berwin B.
Toll-like receptor regulation of scavenger receptor-A-mediated phagocytosis.
J Leukoc Biol. 2008 Dec 26. [Epub ahead of print]
PMID: 19112093 [PubMed - as supplied by publisher]
0622. Abu-Dayyeh I, Shio MT, Sato S, Akira S, Cousineau B, Olivier M.
Leishmania-Induced IRAK-1 Inactivation Is Mediated by SHP-1 Interacting with an Evolutionarily Conserved KTIM Motif.
PLoS Negl Trop Dis. 2008;2(12):e305. Epub 2008 Dec 23.
PMID: 19104650 [PubMed - in process]
0621. Sheahan T, Morrison TE, Funkhouser W, Uematsu S, Akira S, Baric RS, Heise MT.
MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV.
PLoS Pathog. 2008 Dec;4(12):e1000240. Epub 2008 Dec 12.
PMID: 19079579 [PubMed - in process]
0620. Saiga H, Nishimura J, Kuwata H, Okuyama M, Matsumoto S, Sato S, Matsumoto M, Akira S, Yoshikai Y, Honda K, Yamamoto M, Takeda K.
Lipocalin 2-dependent inhibition of mycobacterial growth in alveolar epithelium.
J Immunol. 2008 Dec 15;181(12):8521-7.
PMID: 19050270 [PubMed - indexed for MEDLINE]
0619. Lee PY, Kumagai Y, Li Y, Takeuchi O, Yoshida H, Weinstein J, Kellner ES, Nacionales D, Barker T, Kelly-Scumpia K, van Rooijen N, Kumar H, Kawai T, Satoh M, Akira S, Reeves WH.
TLR7-dependent and FcgammaR-independent production of type I interferon in experimental mouse lupus.
J Exp Med. 2008 Dec 22;205(13):2995-3006. Epub 2008 Dec 1.
PMID: 19047436 [PubMed - indexed for MEDLINE]
0618. Lewis SD, Butchi NB, Khaleduzzaman M, Morgan TW, Du M, Pourciau S, Baker DG, Akira S, Peterson KE.
Toll-like receptor 7 is not necessary for retroviral europathogenesis but does contribute to virus-induced neuroinflammation.
J Neurovirol. 2008 Nov 17:1-11. [Epub ahead of print]
PMID: 19016073 [PubMed - as supplied by publisher]
0617. Allam R, Pawar RD, Kulkarni OP, Hornung V, Hartmann G, Segerer S, Akira S, Endres S, Anders HJ.
Viral 5'-triphosphate RNA and non-CpG DNA aggravate autoimmunity and lupus nephritis via distinct TLR-independent immune responses.
Eur J Immunol. 2008 Dec;38(12):3487-98.
PMID: 19009528 [PubMed - indexed for MEDLINE]
0616. Waibler Z, Anzaghe M, Konur A, Akira S, Muller W, Kalinke U.
Excessive CpG 1668 stimulation triggers IL-10 production by cDC that inhibits IFN-alpha responses by pDC.
Eur J Immunol. 2008 Nov;38(11):3127-37.
PMID: 18991289 [PubMed - indexed for MEDLINE]
0615. Yoshida R, Takaesu G, Yoshida H, Okamoto F, Yoshioka T, Choi Y, Akira S, Kawai T, Yoshimura A, Kobayashi T.
TRAF6 and MEKK1 play a pivotal role in the RIG-I-like helicase antiviral pathway.
J Biol Chem. 2008 Dec 26;283(52):36211-20. Epub 2008 Nov 4.
PMID: 18984593 [PubMed - indexed for MEDLINE]
0614. Poeck H, Besch R, Maihoefer C, Renn M, Tormo D, Morskaya SS, Kirschnek S, Gaffal E, Landsberg J, Hellmuth J, Schmidt A, Anz D, Bscheider M, Schwerd T, Berking C, Bourquin C, Kalinke U, Kremmer E, Kato H, Akira S, Meyers R, Hacker G, Neuenhahn M, Busch D, Ruland J, Rothenfusser S, Prinz M, Hornung V, Endres S, Tuting T, Hartmann G.
5'-Triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma.
Nat Med. 2008 Nov;14(11):1256-63. Epub 2008 Nov 2.
PMID: 18978796 [PubMed - indexed for MEDLINE]
0613. Kawakami A, Osaka M, Aikawa M, Uematsu S, Akira S, Libby P, Shimokado K, Sacks FM, Yoshida M.
Toll-like receptor 2 mediates apolipoprotein CIII-induced monocyte activation.
Circ Res. 2008 Dec 5;103(12):1402-9. Epub 2008 Oct 30.
PMID: 18974386 [PubMed - indexed for MEDLINE]
0612. Selvarajoo K, Takada Y, Gohda J, Helmy M, Akira S, Tomita M, Tsuchiya M, Inoue J, Matsuo K.
Signaling flux redistribution at toll-like receptor pathway junctions.
PLoS ONE. 2008;3(10):e3430. Epub 2008 Oct 17.
PMID: 18927610 [PubMed - indexed for MEDLINE]
0611. Saitoh T, Fujita N, Jang MH, Uematsu S, Yang BG, Satoh T, Omori H, Noda T, Yamamoto N, Komatsu M, Tanaka K, Kawai T, Tsujimura T, Takeuchi O, Yoshimori T, Akira S.
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production.
Nature. 2008 Nov 13;456(7219):264-8. Epub 2008 Oct 5.
PMID: 18849965 [PubMed - indexed for MEDLINE]
0610. Zhu Q, Egelston C, Vivekanandhan A, Uematsu S, Akira S, Klinman DM, Belyakov IM, Berzofsky JA.
Toll-like receptor ligands synergize through distinct dendritic cell pathways to induce T cell responses: implications for vaccines.
Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16260-5. Epub 2008 Oct 9.
PMID: 18845682 [PubMed - indexed for MEDLINE]
0609. Tominaga H, Maeda S, Hayashi M, Takeda S, Akira S, Komiya S, Nakamura T, Akiyama H, Imamura T.
CCAAT/enhancer-binding protein beta promotes osteoblast differentiation by enhancing Runx2 activity with ATF4.
Mol Biol Cell. 2008 Dec;19(12):5373-86. Epub 2008 Oct 8.
PMID: 18843047 [PubMed - indexed for MEDLINE]
0608. Yamazaki S, Matsuo S, Muta T, Yamamoto M, Akira S, Takeshige K.
Gene-specific requirement of a nuclear protein, IkappaB-zeta, for promoter association of inflammatory transcription regulators.
J Biol Chem. 2008 Nov 21;283(47):32404-11. Epub 2008 Sep 29.
PMID: 18824552 [PubMed - indexed for MEDLINE]
0607. Hiratsuka S, Watanabe A, Sakurai Y, Akashi-Takamura S, Ishibashi S, Miyake K, Shibuya M, Akira S, Aburatani H, Maru Y.
The S100A8-serum amyloid A3-TLR4 paracrine cascade establishes a pre-metastatic phase.
Nat Cell Biol. 2008 Nov;10(11):1349-55. Epub 2008 Sep 28.
PMID: 18820689 [PubMed - indexed for MEDLINE]
0606. Nomura T, Miyashita M, Shrestha S, Makino H, Nakamura Y, Aso R, Yoshimura A, Shimura T, Akira S, Tajiri T.
Can interview prior to laparoscopic simulator training predict a trainee's skills?
J Surg Educ. 2008 Sep-Oct;65(5):335-9.
PMID: 18809161 [PubMed - indexed for MEDLINE]
0605. Kariko K, Muramatsu H, Welsh FA, Ludwig J, Kato H, Akira S, Weissman D.
Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability.
Mol Ther. 2008 Nov;16(11):1833-40. Epub 2008 Sep 16.
PMID: 18797453 [PubMed - indexed for MEDLINE]
0604. Huen MS, Huang J, Yuan J, Yamamoto M, Akira S, Ashley C, Xiao W, Chen J.
Noncanonical E2 variant-independent function of UBC13 in promoting checkpoint protein assembly.
Mol Cell Biol. 2008 Oct;28(19):6104-12. Epub 2008 Aug 4.
PMID: 18678647 [PubMed - indexed for MEDLINE]
0603. van Zoelen MA, Yang H, Florquin S, Meijers JC, Akira S, Arnold B, Nawroth PP, Bierhaus A, Tracey KJ, van der Poll T.
ROLE OF TOLL-LIKE RECEPTORS 2 AND 4, AND THE RECEPTOR FOR ADVANCED GLYCATION END PRODUCTS (RAGE) IN HMGB1 INDUCED INFLAMMATION IN VIVO.
Shock. 2008 Jul 24. [Epub ahead of print]
PMID: 18665043 [PubMed - as supplied by publisher]
0602. Leng X, Lin H, Ding T, Wang Y, Wu Y, Klumpp S, Sun T, Zhou Y, Monaco P, Belmont J, Aderem A, Akira S, Strong R, Arlinghaus R.
Lipocalin 2 is required for BCR-ABL-induced tumorigenesis.
Oncogene. 2008 Oct 16;27(47):6110-9. Epub 2008 Jul 28.
PMID: 18663364 [PubMed - indexed for MEDLINE]
0601. Nakamura J, Fujimoto M, Yasuda K, Takeda K, Akira S, Hatayama T, Takagi Y, Nozaki K, Hosokawa N, Nagata K.
Targeted disruption of Hsp110/105 gene protects against ischemic stress.
Stroke. 2008 Oct;39(10):2853-9. Epub 2008 Jul 24.
PMID: 18658041 [PubMed - indexed for MEDLINE]
0600. Nakamura K, Miyazato A, Koguchi Y, Adachi Y, Ohno N, Saijo S, Iwakura Y, Takeda K, Akira S, Fujita J, Ishii K, Kaku M, Kawakami K.
Toll-like receptor 2 (TLR2) and dectin-1 contribute to the production of IL-12p40 by bone marrow-derived dendritic cells infected with Penicillium marneffei.
Microbes Infect. 2008 Aug-Sep;10(10-11):1223-7. Epub 2008 Jul 3.
PMID: 18652908 [PubMed - in process]
0599. Taylor PA, Ehrhardt MJ, Lees CJ, Panoskaltsis-Mortari A, Krieg AM, Sharpe AH, Murphy WJ, Serody JS, Hemmi H, Akira S, Levy RB, Blazar BR.
TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection.
Blood. 2008 Oct 15;112(8):3508-16. Epub 2008 Jul 9.
PMID: 18614760 [PubMed - indexed for MEDLINE]
0598. Herrmann JE, Imura T, Song B, Qi J, Ao Y, Nguyen TK, Korsak RA, Takeda K, Akira S, Sofroniew MV.
STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injury.
J Neurosci. 2008 Jul 9;28(28):7231-43.
PMID: 18614693 [PubMed - indexed for MEDLINE]
0597. Santiago-Raber ML, Kikuchi S, Borel P, Uematsu S, Akira S, Kotzin BL, Izui S.
Evidence for genes in addition to Tlr7 in the Yaa translocation linked with acceleration of systemic lupus erythematosus.
J Immunol. 2008 Jul 15;181(2):1556-62.
PMID: 18606711 [PubMed - indexed for MEDLINE]
0596. Kajino-Sakamoto R, Inagaki M, Lippert E, Akira S, Robine S, Matsumoto K, Jobin C, Ninomiya-Tsuji J.
Enterocyte-derived TAK1 signaling prevents epithelium apoptosis and the development of ileitis and colitis.
J Immunol. 2008 Jul 15;181(2):1143-52.
PMID: 18606667 [PubMed - indexed for MEDLINE]
0595. Kato H, Takeuchi O, Mikamo-Satoh E, Hirai R, Kawai T, Matsushita K, Hiiragi A, Dermody TS, Fujita T, Akira S.
Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5.
J Exp Med. 2008 Jul 7;205(7):1601-10.
PMID: 18591409 [PubMed - indexed for MEDLINE]
0594. Tang M, Wei X, Guo Y, Breslin P, Zhang S, Zhang S, Wei W, Xia Z, Diaz M, Akira S, Zhang J.
TAK1 is required for the survival of hematopoietic cells and hepatocytes in mice.
J Exp Med. 2008 Jul 7;205(7):1611-9. Epub 2008 Jun 23.
PMID: 18573910 [PubMed - indexed for MEDLINE]
0593. Uematsu S, Fujimoto K, Jang MH, Yang BG, Jung YJ, Nishiyama M, Sato S, Tsujimura T, Yamamoto M, Yokota Y, Kiyono H, Miyasaka M, Ishii KJ, Akira S.
Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5.
Nat Immunol. 2008 Jul;9(7):769-76. Epub 2008 May 30.
PMID: 18516037 [PubMed - indexed for MEDLINE]
0592. Ohbayashi N, Okada K, Kawakami S, Togi S, Sato N, Ikeda O, Kamitani S, Muromoto R, Sekine Y, Kawai T, Akira S, Matsuda T.
Physical and functional interactions between ZIP kinase and UbcH5.
Biochem Biophys Res Commun. 2008 Aug 8;372(4):708-12. Epub 2008 Jun 2.
PMID: 18515077 [PubMed - indexed for MEDLINE]
0591. Kobayashi T, Takahashi K, Nagai Y, Shibata T, Otani M, Izui S, Akira S, Gotoh Y, Kiyono H, Miyake K.
Tonic B cell activation by Radioprotective105/MD-1 promotes disease progression in MRL/lpr mice.
Int Immunol. 2008 Jul;20(7):881-91. Epub 2008 May 19.
PMID: 18492657 [PubMed - in process]
0590. Elander N, Ungerback J, Olsson H, Uematsu S, Akira S, Soderkvist P.
Genetic deletion of mPGES-1 accelerates intestinal tumorigenesis in APC(Min/+) mice.
Biochem Biophys Res Commun. 2008 Jul 18;372(1):249-53. Epub 2008 May 15.
PMID: 18485889 [PubMed - indexed for MEDLINE]
0589. Gratz N, Siller M, Schaljo B, Pirzada ZA, Gattermeier I, Vojtek I, Kirschning CJ, Wagner H, Akira S, Charpentier E, Kovarik P.
Group A streptococcus activates type I interferon production and MyD88-dependent signaling without involvement of TLR2, TLR4, and TLR9.
J Biol Chem. 2008 Jul 18;283(29):19879-87. Epub 2008 May 14.
PMID: 18480050 [PubMed - indexed for MEDLINE]
0588. Koga T, Endo H, Miyamoto Y, Mukai M, Akira S, Inoue M.
IGFBPs contribute to survival of pancreatic cancer cells under severely hypoxic conditions.
Cancer Lett. 2008 Sep 8;268(1):82-8. Epub 2008 May 7.
PMID: 18467023 [PubMed - indexed for MEDLINE]
0587. Ueta M, Hamuro J, Ueda E, Katoh N, Yamamoto M, Takeda K, Akira S, Kinoshita S.
Stat6-independent tissue inflammation occurs selectively on the ocular surface and perioral skin of IkappaBzeta-/- mice.
Invest Ophthalmol Vis Sci. 2008 Aug;49(8):3387-94. Epub 2008 Apr 25.
PMID: 18441309 [PubMed - indexed for MEDLINE]
0586. Kawagoe T, Sato S, Matsushita K, Kato H, Matsui K, Kumagai Y, Saitoh T, Kawai T, Takeuchi O, Akira S.
Sequential control of Toll-like receptor-dependent responses by IRAK1 and IRAK2.
Nat Immunol. 2008 Jun;9(6):684-91. Epub 2008 Apr 27.
PMID: 18438411 [PubMed - indexed for MEDLINE]
0585. Zucchini N, Bessou G, Traub S, Robbins SH, Uematsu S, Akira S, Alexopoulou L, Dalod M.
Cutting edge: Overlapping functions of TLR7 and TLR9 for innate defense against a herpesvirus infection.
J Immunol. 2008 May 1;180(9):5799-803.
PMID: 18424698 [PubMed - indexed for MEDLINE]
0584. Imai Y, Kuba K, Neely GG, Yaghubian-Malhami R, Perkmann T, van Loo G, Ermolaeva M, Veldhuizen R, Leung YH, Wang H, Liu H, Sun Y, Pasparakis M, Kopf M, Mech C, Bavari S, Peiris JS, Slutsky AS, Akira S, Hultqvist M, Holmdahl R, Nicholls J, Jiang C, Binder CJ, Penninger JM.
Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury.
Cell. 2008 Apr 18;133(2):235-49.
PMID: 18423196 [PubMed - indexed for MEDLINE]
0583. Gong L, Yao F, Hockman K, Heng HH, Morton GJ, Takeda K, Akira S, Low MJ, Rubinstein M, MacKenzie RG.
Signal transducer and activator of transcription-3 is required in hypothalamic agouti-related protein/neuropeptide Y neurons for normal energy homeostasis.
Endocrinology. 2008 Jul;149(7):3346-54. Epub 2008 Apr 10.
PMID: 18403487 [PubMed - indexed for MEDLINE]
0582. Samuelsson C, Hausmann J, Lauterbach H, Schmidt M, Akira S, Wagner H, Chaplin P, Suter M, O'Keeffe M, Hochrein H.
Survival of lethal poxvirus infection in mice depends on TLR9, and therapeutic vaccination provides protection.
J Clin Invest. 2008 May;118(5):1776-84.
PMID: 18398511 [PubMed - indexed for MEDLINE]
0581. Tomita T, Kanai T, Fujii T, Nemoto Y, Okamoto R, Tsuchiya K, Totsuka T, Sakamoto N, Akira S, Watanabe M.
MyD88-dependent pathway in T cells directly modulates the expansion of colitogenic CD4+ T cells in chronic colitis.
J Immunol. 2008 Apr 15;180(8):5291-9.
PMID: 18390710 [PubMed - indexed for MEDLINE]
0580. Savarese E, Steinberg C, Pawar RD, Reindl W, Akira S, Anders HJ, Krug A.
Requirement of Toll-like receptor 7 for pristane-induced production of autoantibodies and development of murine lupus nephritis.
Arthritis Rheum. 2008 Apr;58(4):1107-15.
PMID: 18383384 [PubMed - indexed for MEDLINE]
0579. Shin OS, Isberg RR, Akira S, Uematsu S, Behera AK, Hu LT.
Distinct roles for MyD88 and Toll-like receptors 2, 5, and 9 in phagocytosis of Borrelia burgdorferi and cytokine induction.
Infect Immun. 2008 Jun;76(6):2341-51. Epub 2008 Mar 31.
PMID: 18378636 [PubMed - indexed for MEDLINE]
0578. Hirata N, Yanagawa Y, Ebihara T, Seya T, Uematsu S, Akira S, Hayashi F, Iwabuchi K, Onoe K.
Selective synergy in anti-inflammatory cytokine production upon cooperated signaling via TLR4 and TLR2 in murine conventional dendritic cells.
Mol Immunol. 2008 May;45(10):2734-42. Epub 2008 Mar 26.
PMID: 18372043 [PubMed - indexed for MEDLINE]
0577. Obata K, Katsura H, Miyoshi K, Kondo T, Yamanaka H, Kobayashi K, Dai Y, Fukuoka T, Akira S, Noguchi K.
Toll-like receptor 3 contributes to spinal glial activation and tactile allodynia after nerve injury.
J Neurochem. 2008 Apr 9. [Epub ahead of print]
PMID: 18363823 [PubMed - as supplied by publisher]
0576. Nakamura K, Miyazato A, Xiao G, Hatta M, Inden K, Aoyagi T, Shiratori K, Takeda K, Akira S, Saijo S, Iwakura Y, Adachi Y, Ohno N, Suzuki K, Fujita J, Kaku M, Kawakami K.
Deoxynucleic acids from Cryptococcus neoformans activate myeloid dendritic cells via a TLR9-dependent pathway.
J Immunol. 2008 Mar 15;180(6):4067-74.
PMID: 18322216 [PubMed - indexed for MEDLINE]
0575. Nishimura J, Saiga H, Sato S, Okuyama M, Kayama H, Kuwata H, Matsumoto S, Nishida T, Sawa Y, Akira S, Yoshikai Y, Yamamoto M, Takeda K.
Potent antimycobacterial activity of mouse secretory leukocyte protease inhibitor.
J Immunol. 2008 Mar 15;180(6):4032-9.
PMID: 18322212 [PubMed - indexed for MEDLINE]
0574. Kagan JC, Su T, Horng T, Chow A, Akira S, Medzhitov R.
TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta.
Nat Immunol. 2008 Apr;9(4):361-8. Epub 2008 Feb 24.
PMID: 18297073 [PubMed - indexed for MEDLINE]
0573. Holscher C, Reiling N, Schaible UE, Holscher A, Bathmann C, Korbel D, Lenz I, Sonntag T, Kroger S, Akira S, Mossmann H, Kirschning CJ, Wagner H, Freudenberg M, Ehlers S.
Containment of aerogenic Mycobacterium tuberculosis infection in mice does not require MyD88 adaptor function for TLR2, -4 and -9.
Eur J Immunol. 2008 Mar;38(3):680-94.
PMID: 18266299 [PubMed - indexed for MEDLINE]
0572. Ishii KJ, Kawagoe T, Koyama S, Matsui K, Kumar H, Kawai T, Uematsu S, Takeuchi O, Takeshita F, Coban C, Akira S.
TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines.
Nature. 2008 Feb 7;451(7179):725-9.
PMID: 18256672 [PubMed - indexed for MEDLINE]
0571. Zhang B, Ramesh G, Uematsu S, Akira S, Reeves WB.
TLR4 signaling mediates inflammation and tissue injury in nephrotoxicity.
J Am Soc Nephrol. 2008 May;19(5):923-32. Epub 2008 Feb 6.
PMID: 18256356 [PubMed - indexed for MEDLINE]
0570. Hisaeda H, Tetsutani K, Imai T, Moriya C, Tu L, Hamano S, Duan X, Chou B, Ishida H, Aramaki A, Shen J, Ishii KJ, Coban C, Akira S, Takeda K, Yasutomo K, Torii M, Himeno K.
Malaria parasites require TLR9 signaling for immune evasion by activating regulatory T cells.
J Immunol. 2008 Feb 15;180(4):2496-503.
PMID: 18250459 [PubMed - indexed for MEDLINE]
0569. Nakano Y, Kuroda E, Kito T, Uematsu S, Akira S, Yokota A, Nishizawa S, Yamashita U.
Induction of prostaglandin E2 synthesis and microsomal prostaglandin E synthase-1 expression in murine microglia by glioma-derived soluble factors. Laboratory investigation.
J Neurosurg. 2008 Feb;108(2):311-9.
PMID: 18240928 [PubMed - indexed for MEDLINE]
0568. Bhattacharjee RN, Park KS, Chen X, Iida T, Honda T, Takeuchi O, Akira S.
Translocation of VP1686 upregulates RhoB and accelerates phagocytic activity of macrophage through actin remodeling.
J Microbiol Biotechnol. 2008 Jan;18(1):171-5.
PMID: 18239436 [PubMed - indexed for MEDLINE]
0567. Foster GL, Barr TA, Grant AJ, McKinley TJ, Bryant CE, MacDonald A, Gray D, Yamamoto M, Akira S, Maskell DJ, Mastroeni P.
Virulent Salmonella enterica infections can be exacerbated by concomitant infection of the host with a live attenuated S. enterica vaccine via Toll-like receptor 4-dependent interleukin-10 production with the involvement of both TRIF and MyD88.
Immunology. 2008 Aug;124(4):469-79. Epub 2008 Feb 1.
PMID: 18217948 [PubMed - indexed for MEDLINE]
0566. Chang SY, Cha HR, Uematsu S, Akira S, Igarashi O, Kiyono H, Kweon MN.
Colonic patches direct the cross-talk between systemic compartments and large intestine independently of innate immunity.
J Immunol. 2008 Feb 1;180(3):1609-18.
PMID: 18209057 [PubMed - indexed for MEDLINE]
0565. Vijay-Kumar M, Aitken JD, Kumar A, Neish AS, Uematsu S, Akira S, Gewirtz AT.
Toll-like receptor 5-deficient mice have dysregulated intestinal gene expression and nonspecific resistance to Salmonella-induced typhoid-like disease.
Infect Immun. 2008 Mar;76(3):1276-81. Epub 2008 Jan 14.
PMID: 18195036 [PubMed - indexed for MEDLINE]
0564. Escors D, Lopes L, Lin R, Hiscott J, Akira S, Davis RJ, Collins MK.
Targeting dendritic cell signaling to regulate the response to immunization.
Blood. 2008 Mar 15;111(6):3050-61. Epub 2008 Jan 7.
PMID: 18180378 [PubMed - indexed for MEDLINE]
0563. Kumar H, Koyama S, Ishii KJ, Kawai T, Akira S.
Cutting edge: cooperation of IPS-1- and TRIF-dependent pathways in poly IC-enhanced antibody production and cytotoxic T cell responses.
J Immunol. 2008 Jan 15;180(2):683-7.
PMID: 18178804 [PubMed - indexed for MEDLINE]
0562. Swann JB, Vesely MD, Silva A, Sharkey J, Akira S, Schreiber RD, Smyth MJ.
Demonstration of inflammation-induced cancer and cancer immunoediting during primary tumorigenesis.
Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):652-6. Epub 2008 Jan 4.
PMID: 18178624 [PubMed - indexed for MEDLINE]
0561. Stenzel W, Soltek S, Sanchez-Ruiz M, Akira S, Miletic H, Schluter D, Deckert M.
Both TLR2 and TLR4 are required for the effective immune response in Staphylococcus aureus-induced experimental murine brain abscess.
Am J Pathol. 2008 Jan;172(1):132-45. Epub 2007 Dec 28.
PMID: 18165267 [PubMed - indexed for MEDLINE]
0560. Yamakawa K, Kamekura S, Kawamura N, Saegusa M, Kamei D, Murakami M, Kudo I, Uematsu S, Akira S, Chung UI, Nakamura K, Kawaguchi H.
Association of microsomal prostaglandin E synthase 1 deficiency with impaired fracture healing, but not with bone loss or osteoarthritis, in mouse models of skeletal disorders.
Arthritis Rheum. 2008 Jan;58(1):172-83.
PMID: 18163499 [PubMed - indexed for MEDLINE]
0559. Noor S, Goldfine H, Tucker DE, Suram S, Lenz LL, Akira S, Uematsu S, Girotti M, Bonventre JV, Breuel K, Williams DL, Leslie CC.
Activation of cytosolic phospholipase A2alpha in resident peritoneal macrophages by Listeria monocytogenes involves listeriolysin O and TLR2.
J Biol Chem. 2008 Feb 22;283(8):4744-55. Epub 2007 Dec 14.
PMID: 18083708 [PubMed - indexed for MEDLINE]
0558. Goto A, Matsushita K, Gesellchen V, El Chamy L, Kuttenkeuler D, Takeuchi O, Hoffmann JA, Akira S, Boutros M, Reichhart JM.
Akirins are highly conserved nuclear proteins required for NF-kappaB-dependent gene expression in drosophila and mice.
Nat Immunol. 2008 Jan;9(1):97-104. Epub 2007 Dec 9. Erratum in: Nat Immunol. 2008 Feb;9(2):216.
PMID: 18066067 [PubMed - indexed for MEDLINE]
0557. Abdollahi-Roodsaz S, Joosten LA, Koenders MI, Devesa I, Roelofs MF, Radstake TR, Heuvelmans-Jacobs M, Akira S, Nicklin MJ, Ribeiro-Dias F, van den Berg WB.
Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis.
J Clin Invest. 2008 Jan;118(1):205-16.
PMID: 18060042 [PubMed - indexed for MEDLINE]
0556. Akagi T, Saitoh T, O'Kelly J, Akira S, Gombart AF, Koeffler HP.
Impaired response to GM-CSF and G-CSF, and enhanced apoptosis in C/EBPbeta-deficient hematopoietic cells.
Blood. 2008 Mar 15;111(6):2999-3004. Epub 2007 Dec 4.
PMID: 18056834 [PubMed - indexed for MEDLINE]
0555. Yang CS, Shin DM, Lee HM, Son JW, Lee SJ, Akira S, Gougerot-Pocidalo MA, El-Benna J, Ichijo H, Jo EK.
ASK1-p38 MAPK-p47phox activation is essential for inflammatory responses during tuberculosis via TLR2-ROS signalling.
Cell Microbiol. 2008 Mar;10(3):741-54. Epub 2007 Nov 19.
PMID: 18028450 [PubMed - indexed for MEDLINE]
0554. Wilson NS, Young LJ, Kupresanin F, Naik SH, Vremec D, Heath WR, Akira S, Shortman K, Boyle J, Maraskovsky E, Belz GT, Villadangos JA.
Normal proportion and expression of maturation markers in migratory dendritic cells in the absence of germs or Toll-like receptor signaling.
Immunol Cell Biol. 2008 Feb;86(2):200-5. Epub 2007 Nov 20.
PMID: 18026177 [PubMed - indexed for MEDLINE]
0553. Sugiyama T, Hoshino K, Saito M, Yano T, Sasaki I, Yamazaki C, Akira S, Kaisho T.
Immunoadjuvant effects of polyadenylic:polyuridylic acids through TLR3 and TLR7.
Int Immunol. 2008 Jan;20(1):1-9. Epub 2007 Nov 1.
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