0144. Toda K, Takeda K, Akira S, Saibara T, Okada T, Onishi S, Shizuta Y.
Alternations in hepatic expression of fatty-acid metabolizing enzymes in ArKO mice and their reversal by the treatment with 17beta-estradiol or a peroxisome proliferator.
J Steroid Biochem Mol Biol. 2001 Dec;79(1-5):11-7.
PMID: 11850202 [PubMed - indexed for MEDLINE]
0143. Henneke P, Takeuchi O, van Strijp JA, Guttormsen HK, Smith JA, Schromm AB, Espevik TA, Akira S, Nizet V, Kasper DL, Golenbock DT.
Novel engagement of CD14 and multiple toll-like receptors by group B streptococci.
J Immunol. 2001 Dec 15;167(12):7069-76.
PMID: 11739528 [PubMed - indexed for MEDLINE]
0142. Nomi M, Oishi I, Kani S, Suzuki H, Matsuda T, Yoda A, Kitamura M, Itoh K, Takeuchi S, Takeda K, Akira S, Ikeya M, Takada S, Minami Y.
Loss of mRor1 enhances the heart and skeletal abnormalities in mRor2-deficient mice: redundant and pleiotropic functions of mRor1 and mRor2 receptor tyrosine kinases.
Mol Cell Biol. 2001 Dec;21(24):8329-35.
PMID: 11713269 [PubMed - indexed for MEDLINE]
0141. Adachi K, Tsutsui H, Kashiwamura S, Seki E, Nakano H, Takeuchi O, Takeda K, Okumura K, Van Kaer L, Okamura H, Akira S, Nakanishi K.
Plasmodium berghei infection in mice induces liver injury by an IL-12- and toll-like receptor/myeloid differentiation factor 88-dependent mechanism.
J Immunol. 2001 Nov 15;167(10):5928-34.
PMID: 11698470 [PubMed - indexed for MEDLINE]
0140. Kawai T, Takeuchi O, Fujita T, Inoue J, Muhlradt PF, Sato S, Hoshino K, Akira S.
Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes.
J Immunol. 2001 Nov 15;167(10):5887-94.
PMID: 11698465 [PubMed - indexed for MEDLINE]
0139. Kanai T, Watanabe M, Okazawa A, Sato T, Yamazaki M, Okamoto S, Ishii H, Totsuka T, Iiyama R, Okamoto R, Ikeda M, Kurimoto M, Takeda K, Akira S, Hibi T.
Macrophage-derived IL-18-mediated intestinal inflammation in the murine model of Crohn's disease.
Gastroenterology. 2001 Oct;121(4):875-88.
PMID: 11606501 [PubMed - indexed for MEDLINE]
0138. Kawakami K, Kinjo Y, Yara S, Uezu K, Koguchi Y, Tohyama M, Azuma M, Takeda K, Akira S, Saito A.
Enhanced gamma interferon production through activation of Valpha14(+) natural killer T cells by alpha-galactosylceramide in interleukin-18-deficient mice with systemic cryptococcosis.
Infect Immun. 2001 Nov;69(11):6643-50.
PMID: 11598033 [PubMed - indexed for MEDLINE]
0137. Kawashima T, Murata K, Akira S, Tonozuka Y, Minoshima Y, Feng S, Kumagai H, Tsuruga H, Ikeda Y, Asano S, Nosaka T, Kitamura T.
STAT5 induces macrophage differentiation of M1 leukemia cells through activation of IL-6 production mediated by NF-kappaB p65.
J Immunol. 2001 Oct 1;167(7):3652-60.
PMID: 11564778 [PubMed - indexed for MEDLINE]
0136. Schnare M, Barton GM, Holt AC, Takeda K, Akira S, Medzhitov R.
Toll-like receptors control activation of adaptive immune responses.
Nat Immunol. 2001 Oct;2(10):947-50.
PMID: 11547333 [PubMed - indexed for MEDLINE]
0135. Oyadomari S, Takeda K, Takiguchi M, Gotoh T, Matsumoto M, Wada I, Akira S, Araki E, Mori M.
Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway.
Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10845-50. Epub 2001 Aug 28.
PMID: 11526215 [PubMed - indexed for MEDLINE]
0134. Byrd-Leifer CA, Block EF, Takeda K, Akira S, Ding A.
The role of MyD88 and TLR4 in the LPS-mimetic activity of Taxol.
Eur J Immunol. 2001 Aug;31(8):2448-57.
PMID: 11500829 [PubMed - indexed for MEDLINE]
0133. Helmby H, Takeda K, Akira S, Grencis RK.
Interleukin (IL)-18 promotes the development of chronic gastrointestinal helminth infection by downregulating IL-13.
J Exp Med. 2001 Aug 6;194(3):355-64.
PMID: 11489954 [PubMed - indexed for MEDLINE]
0132. Bauer S, Kirschning CJ, Hacker H, Redecke V, Hausmann S, Akira S, Wagner H, Lipford GB.
Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition.
Proc Natl Acad Sci U S A. 2001 Jul 31;98(16):9237-42. Epub 2001 Jul 24.
PMID: 11470918 [PubMed - indexed for MEDLINE]
0131. Sugawara S, Yang S, Iki K, Hatakeyama J, Tamai R, Takeuchi O, Akashi S, Espevik T, Akira S, Takada H.
Monocytic cell activation by Nonendotoxic glycoprotein from Prevotella intermedia ATCC 25611 is mediated by toll-like receptor 2.
Infect Immun. 2001 Aug;69(8):4951-7.
PMID: 11447173 [PubMed - indexed for MEDLINE]
0130. Takeuchi O, Kawai T, Muhlradt PF, Morr M, Radolf JD, Zychlinsky A, Takeda K, Akira S.
Discrimination of bacterial lipoproteins by Toll-like receptor 6.
Int Immunol. 2001 Jul;13(7):933-40.
PMID: 11431423 [PubMed - indexed for MEDLINE]
0129. Toda K, Takeda K, Okada T, Akira S, Saibara T, Kaname T, Yamamura K, Onishi S, Shizuta Y.
Targeted disruption of the aromatase P450 gene (Cyp19) in mice and their ovarian and uterine responses to 17beta-oestradiol.
J Endocrinol. 2001 Jul;170(1):99-111.
PMID: 11431142 [PubMed - indexed for MEDLINE]
0128. Campos MA, Almeida IC, Takeuchi O, Akira S, Valente EP, Procopio DO, Travassos LR, Smith JA, Golenbock DT, Gazzinelli RT.
Activation of Toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasite.
J Immunol. 2001 Jul 1;167(1):416-23.
PMID: 11418678 [PubMed - indexed for MEDLINE]
0127. Mahalingam S, Karupiah G, Takeda K, Akira S, Matthaei KI, Foster PS.
Enhanced resistance in STAT6-deficient mice to infection with ectromelia virus.
Proc Natl Acad Sci U S A. 2001 Jun 5;98(12):6812-7. Epub 2001 May 22.
PMID: 11371617 [PubMed - indexed for MEDLINE]
0126. Hayashi F, Smith KD, Ozinsky A, Hawn TR, Yi EC, Goodlett DR, Eng JK, Akira S, Underhill DM, Aderem A.
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5.
Nature. 2001 Apr 26;410(6832):1099-103.
PMID: 11323673 [PubMed - indexed for MEDLINE]
0125. Kaisho T, Takeuchi O, Kawai T, Hoshino K, Akira S.
Endotoxin-induced maturation of MyD88-deficient dendritic cells.
J Immunol. 2001 May 1;166(9):5688-94.
PMID: 11313410 [PubMed - indexed for MEDLINE]
0124. Kimura T, Chowdhury S, Tanaka T, Shimizu A, Iwase K, Oyadomari S, Gotoh T, Matsuzaki H, Mori M, Akira S, Takiguchi M.
CCAAT/enhancer-binding protein beta is required for activation of genes for ornithine cycle enzymes by glucocorticoids and glucagon in primary-cultured hepatocytes.
FEBS Lett. 2001 Apr 6;494(1-2):105-11.
PMID: 11297744 [PubMed - indexed for MEDLINE]
0123. Yang S, Tamai R, Akashi S, Takeuchi O, Akira S, Sugawara S, Takada H.
Synergistic effect of muramyldipeptide with lipopolysaccharide or lipoteichoic acid to induce inflammatory cytokines in human monocytic cells in culture.
Infect Immun. 2001 Apr;69(4):2045-53.
PMID: 11254557 [PubMed - indexed for MEDLINE]
0122. Toda K, Okada T, Takeda K, Akira S, Saibara T, Shiraishi M, Onishi S, Shizuta Y.
Oestrogen at the neonatal stage is critical for the reproductive ability of male mice as revealed by supplementation with 17beta-oestradiol to aromatase gene(Cyp19) knockout mice.
J Endocrinol. 2001 Mar;168(3):455-63.
PMID: 11241177 [PubMed - indexed for MEDLINE]
0121. Matsushima A, Kaisho T, Rennert PD, Nakano H, Kurosawa K, Uchida D, Takeda K, Akira S, Matsumoto M.
Essential role of nuclear factor (NF)-kappaB-inducing kinase and inhibitor of kappaB (IkappaB) kinase alpha in NF-kappaB activation through lymphotoxin beta receptor, but not through tumor necrosis factor receptor I.
J Exp Med. 2001 Mar 5;193(5):631-6.
PMID: 11238593 [PubMed - indexed for MEDLINE]
0120. Thoma-Uszynski S, Stenger S, Takeuchi O, Ochoa MT, Engele M, Sieling PA, Barnes PF, Rollinghoff M, Bolcskei PL, Wagner M, Akira S, Norgard MV, Belisle JT, Godowski PJ, Bloom BR, Modlin RL.
Induction of direct antimicrobial activity through mammalian toll-like receptors.
Science. 2001 Feb 23;291(5508):1544-7.
PMID: 11222859 [PubMed - indexed for MEDLINE]
0119. Filipp D, Alizadeh-Khiavi K, Richardson C, Palma A, Paredes N, Takeuchi O, Akira S, Julius M.
Soluble CD14 enriched in colostrum and milk induces B cell growth and differentiation.
Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):603-8.
PMID: 11209057 [PubMed - indexed for MEDLINE]
0118. Kawazoe Y, Naka T, Fujimoto M, Kohzaki H, Morita Y, Narazaki M, Okumura K, Saitoh H, Nakagawa R, Uchiyama Y, Akira S, Kishimoto T.
Signal transducer and activator of transcription (STAT)-induced STAT inhibitor 1 (SSI-1)/suppressor of cytokine signaling 1 (SOCS1) inhibits insulin signal transduction pathway through modulating insulin receptor substrate 1 (IRS-1) phosphorylation.
J Exp Med. 2001 Jan 15;193(2):263-9.
PMID: 11208867 [PubMed - indexed for MEDLINE]
0117. Suzuki A, Hanada T, Mitsuyama K, Yoshida T, Kamizono S, Hoshino T, Kubo M, Yamashita A, Okabe M, Takeda K, Akira S, Matsumoto S, Toyonaga A, Sata M, Yoshimura A.
CIS3/SOCS3/SSI3 plays a negative regulatory role in STAT3 activation and intestinal inflammation.
J Exp Med. 2001 Feb 19;193(4):471-81.
PMID: 11181699 [PubMed - indexed for MEDLINE]
0116. Kaisho T, Takeda K, Tsujimura T, Kawai T, Nomura F, Terada N, Akira S.
IkappaB kinase alpha is essential for mature B cell development and function.
J Exp Med. 2001 Feb 19;193(4):417-26.
PMID: 11181694 [PubMed - indexed for MEDLINE]
0115. Seki E, Tsutsui H, Nakano H, Tsuji N, Hoshino K, Adachi O, Adachi K, Futatsugi S, Kuida K, Takeuchi O, Okamura H, Fujimoto J, Akira S, Nakanishi K.
Lipopolysaccharide-induced IL-18 secretion from murine Kupffer cells independently of myeloid differentiation factor 88 that is critically involved in induction of production of IL-12 and IL-1beta.
J Immunol. 2001 Feb 15;166(4):2651-7.
PMID: 11160328 [PubMed - indexed for MEDLINE]
0114. Nishiguchi M, Matsumoto M, Takao T, Hoshino M, Shimonishi Y, Tsuji S, Begum NA, Takeuchi O, Akira S, Toyoshima K, Seya T.
Mycoplasma fermentans lipoprotein M161Ag-induced cell activation is mediated by Toll-like receptor 2: role of N-terminal hydrophobic portion in its multiple functions.
J Immunol. 2001 Feb 15;166(4):2610-6.
PMID: 11160323 [PubMed - indexed for MEDLINE]
0113. Sugawara I, Mizuno S, Yamada H, Matsumoto M, Akira S.
Disruption of nuclear factor-interleukin-6, a transcription factor, results in severe mycobacterial infection.
Am J Pathol. 2001 Feb;158(2):361-6.
PMID: 11159172 [PubMed - indexed for MEDLINE]
0112. Perera PY, Mayadas TN, Takeuchi O, Akira S, Zaks-Zilberman M, Goyert SM, Vogel SN.
CD11b/CD18 acts in concert with CD14 and Toll-like receptor (TLR) 4 to elicit full lipopolysaccharide and taxol-inducible gene expression.
J Immunol. 2001 Jan 1;166(1):574-81.
PMID: 11123339 [PubMed - indexed for MEDLINE]

ページトップへ