Akira Lab. Osaka University (IFReC/RIMD)

Topics

• 2011.04.26

  

  Fujimoto K, Karuppuchamy T, Takemura N, Shimohigoshi M, Machida T, Haseda Y, Aoshi T, Ishii KJ, Akira S, Uematsu S. 
  A New Subset of CD103+CD8{alpha}+ Dendritic Cells in the Small Intestine Expresses TLR3, TLR7, and TLR9 and Induces Th1 Response and CTL Activity. 
  J Immunol. 2011 Apr 27. [Epub ahead of print]
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• 2011.03.25

  

  Antiviral protein Viperin promotes Toll-like receptor 7- and Toll-like receptor 9-mediated type I interferon production in plasmacytoid dendritic cells. Saitoh T, Satoh T, Yamamoto N, Uematsu S, Takeuchi O, Kawai T, Akira S. Immunity. 2011 Mar 25;34(3):352-63.
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• 2010.12.08

  

  NLRC5 Deficiency Does Not Influence Cytokine Induction by Virus and Bacteria Infections

  
  

  Kumar H, Pandey S, Zou J, Kumagai Y, Takahashi K, Akira S, Kawai T.

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• 2010.11.12

  

  The Ubiquitin Ligase TRIM56 Regulates Innate Immune Responses to Intracellular Double-Stranded DNA.
  Tsuchida T, Zou J, Saitoh T, Kumar H, Abe T, Matsuura Y, Kawai T, Akira S.
  Immunity. 2010 Nov 10. [Epub ahead of print]
  

  
  
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• 2010.10.08

  

  I{kappa}B{zeta} is essential for natural killer cell activation in response to IL-12 and IL-18. Miyake T, Satoh T, Kato H, Matsushita K, Kumagai Y, Vandenbon A, Tani T, Muta T, Akira S, Takeuchi O. 
  Proc Natl Acad Sci U S A. 2010 Sep 27. [Epub ahead of print]　
  
  
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• 2010.08.22

  

  The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection.
  Satoh T, Takeuchi O, Vandenbon A, Yasuda K, Tanaka Y, Kumagai Y, Miyake T, Matsushita K, Okazaki T, Saitoh T, Honma K, Matsuyama T, Yui K, Tsujimura T, Standley DM, Nakanishi K, Nakai K, Akira S.
  Nat Immunol. 2010 Aug 22. [Epub ahead of print]

  
  
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• 2010.01.09

  

  LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses
  
  

  Takashi Satoh, Hiroki Kato, Yutaro Kumagai, Mitsutoshi Yoneyama, Shintaro Sato, Kazufumi Matsushita, Tohru Tsujimura, Takashi Fujita, Shizuo Akira and Osamu Takeuchi

  
  

  PNAS

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• 2009.12.15.

  

  Involvement of the NLRP3 Inflammasome in Innate and Humoral Adaptive Immune Responses to Fungal β-Glucan

  Himanshu Kumar, Yutaro Kumagai, Tetsuo Tsuchida, Paul A. Koenig, Takashi Satoh, Zijin Guo, Myoung Ho Jang, Tatsuya Saitoh, Shizuo Akira, and Taro Kawai 

  J Immunol 2009 183: 8061-8067

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• 2009.11.20

  
  
  
  Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response. Saitoh T*, Fujita N*, Hayashi T, Takahara K, Satoh T, Lee H, Matsunaga K, Kageyama S, Omori H, Noda T, Yamamoto N, Kawai T, Ishii K, Takeuchi O, Yoshimori T, Akira S. Proc Natl Acad Sci U S A. 2009 Nov 19. [Epub ahead of print] 
  *These authors equally contributed to this work 
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• 2009.08.12

  

  Kawagoe T*, Takeuchi O*, Takabatake Y, Kato H, Isaka Y, Tsujimura T, Akira S.

  TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis.

  Nat Immunol. 2009 Sep;10(9):965-72.

  *Contributed equally.

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